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Generally, it refers to esomeprazole enteric coated tablets, which are suitable for inhibiting the secretion of gastric acid. The tablets should be swallowed together with the liquid, and should not be chewed or crushed. Nexium generally refers to esomeprazole enteric coated tablets, which are suitable for the treatment of gastroesophageal reflux disease (GERD) - erosive reflux esophagitis - the maintenance treatment to prevent recurrence of recovered esophagitis patients - gastroesophageal reflux disease (GER D) Symptom control combined with appropriate antimicrobial therapy for Helicobacter pylori eradication and - healing of duodenal ulcer associated with Helicobacter pylori infection - prevention of recurrence of peptic ulcer associated with Helicobacter pylori. It is forbidden to use esomeprazole, other benzimidazoles or any other ingredients of the product if it is known to be allergic. Note 1. In case of any alarm symptoms (such as significant unconscious weight loss, repeated vomiting, dysphagia, hematemesis or black stool), suspected gastric ulcer or gastric ulcer, malignant tumor should be excluded, because the use of esomeprazole enteric coated tablets can reduce symptoms and delay diagnosis. 2. Patients treated with the drug (especially those who have used it for more than 1 year) should be monitored regularly. 3. Patients who need to be treated should be informed to contact doctors when their symptoms and characteristics change. In the treatment of on-demand medication, the possible drug interactions due to the fluctuation of esomeprazole blood concentration should be considered (see drug interactions). 4. When esomeprazole is used to remove Helicobacter pylori, the possible drug interactions of all components in triple therapy should be considered. Clarithromycin is an effective inhibitor of CYP3A4. Therefore, when patients take other drugs metabolized by CYP3A4, such as cisapride, the taboo and interaction of clarithromycin should be considered. 5. Patients with rare genetic diseases, such as poor glucose tolerance, glucose galactose absorption disorder or sucrase isomaltase deficiency, should not take this product. 6. Renal function damage: Patients with renal function damage do not need to adjust the dose. For patients with severe renal insufficiency, due to the limited experience of using the drug, the treatment should be cautious (see [pharmacokinetics]). 7. There is no need to adjust the dosage in patients with mild to moderate liver function damage. The dose of esomeprazole enteric coated tablets should not exceed 20 mg in patients with severe liver function damage (see [pharmacokinetics]). 8. The impact on the ability to drive and use the machine has not been observed.

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